Material Safety Data Sheet
    Adrenaline
ACC# 08641
  
    | Section 1 - Chemical Product and Company Identification | 
MSDS Name: Adrenaline
Catalog Numbers:
     S70186
Synonyms:
     Epinephrine; Adrenal; 1-Adrenaline; Adrenasol
Company Identification:
 
 
 
 
 
 
 
Fisher Scientific
 
 
 
 
 
 
 
1 Reagent Lane
 
 
 
 
 
 
 
Fair Lawn, NJ  07410
For information, call:  201-796-7100
Emergency Number:       201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
  
    | Section 2 - Composition, Information on Ingredients | 
  | CAS# | Chemical Name | Percent | EINECS/ELINCS | 
| 51-43-4 | 1,2-benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl] | 100% | 200-098-7 | 
  
    | Section 3 - Hazards Identification | 
EMERGENCY OVERVIEW
Appearance: white solid.
 Warning! Toxic. Harmful if swallowed. May cause
eye and skin irritation. May cause respiratory and digestive tract
irritation. May cause cardiac disturbances. May cause adverse
reproductive effects based upon animal studies.
Target Organs: Heart.
Potential Health Effects
     
Eye:
          May cause eye irritation.  No information regarding eye irritation
          and other potential effects was found.
     
Skin:
          May cause skin irritation. No information regarding skin irritation
          and other potential effects was found.
     
Ingestion:
          Causes gastrointestinal irritation with nausea, vomiting and
          diarrhea.
          May cause cardiovascular effects including increased pulse rate,
          arrythmias, and heart
     
Inhalation:
          May cause respiratory tract irritation. Overexposure may cause
          dizziness, tremors, restlessness, rapid heart beat, increased blood
          pressure, hallucinations, acidosis, kidney failure.
     
Chronic:
          Not available.
  
    | Section 4 - First Aid Measures | 
     
Eyes:
          Flush eyes with plenty of water for at least 15 minutes, occasionally
          lifting the upper and lower eyelids. Get medical aid.
     
Skin:
          Get medical aid. Flush skin with plenty of water for at least 15
          minutes while removing contaminated clothing and shoes.
     
Ingestion:
          If victim is conscious and alert, give 2-4 cupfuls of milk or water.
          Never give anything by mouth to an unconscious person. Get medical
          aid immediately.
     
Inhalation:
          Remove from exposure and move to fresh air immediately. If not
          breathing, give artificial respiration. If breathing is difficult,
          give oxygen. Get medical aid.
     
Notes to Physician:
          Treat symptomatically and supportively.
  
    | Section 5 - Fire Fighting Measures | 
     
General Information:
          As in any fire, wear a self-contained breathing apparatus in
          pressure-demand, MSHA/NIOSH (approved or equivalent), and full
          protective gear.
     
Extinguishing Media:
          For small fires, use water spray, dry chemical, carbon dioxide or
          chemical foam.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
                  Upper: Not available.
     
NFPA Rating:
Not published.
  
    | Section 6 - Accidental Release Measures | 
     
General Information: Use proper personal protective equipment as indicated
                          in Section 8.
     
Spills/Leaks:
          Sweep up or absorb material, then place into a suitable clean, dry,
          closed container for disposal. Avoid generating dusty conditions.
  
    | Section 7 - Handling and Storage | 
     
Handling:
          Wash thoroughly after handling. Wash hands before eating. Remove
          contaminated clothing and wash before reuse. Use with adequate
          ventilation. Do not get on skin or in eyes. Do not ingest or inhale.
     
Storage:
          Keep away from heat and flame. Store in a cool, dry, well-ventilated
          area away from incompatible substances. Keep containers tightly
          closed.
  
    | Section 8 - Exposure Controls, Personal Protection | 
     
Engineering Controls:
          Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
  | Chemical Name | ACGIH | NIOSH | OSHA - Final PELs | 
| 1,2-benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl] | none listed | none listed | none listed | 
     
OSHA Vacated PELs:
          1,2-benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]:
             No OSHA Vacated PELs are listed for this chemical.
     
Personal Protective Equipment
                 
Eyes:
                       Wear appropriate protective eyeglasses or chemical
                       safety goggles as described by OSHA's eye and face
                       protection regulations in 29 CFR 1910.133 or European
                       Standard EN166.
                 
Skin:
                       Wear appropriate protective gloves to prevent skin
                       exposure.
             
Clothing:
                       Wear appropriate protective clothing to prevent skin
                       exposure.
          
Respirators:
                       Follow the OSHA respirator regulations found in 29
                       CFR 1910.134 or European Standard EN 149. Use a
                       NIOSH/MSHA or European Standard EN 149 approved
                       respirator if exposure limits are exceeded or if
                       irritation or other symptoms are experienced.
  
    | Section 9 - Physical and Chemical Properties | 
Physical State:  Solid
Appearance:      white
Odor:            odorless
pH:              Not available.
Vapor Pressure:  Not available.
Vapor Density:   Not available.
Evaporation Rate:Not available.
Viscosity:       Not available.
Boiling Point:   Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility:      Not available.
Specific Gravity/Density:Not available.
Molecular Formula:C9H14ClNO3
Molecular Weight:219.5559
  
    | Section 10 - Stability and Reactivity | 
     
Chemical Stability:
          Stable under normal temperatures and pressures.
     
Conditions to Avoid:
          Incompatible materials.
     
Incompatibilities with Other Materials:
          Strong oxidizers.
     
Hazardous Decomposition Products:
          Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
     
Hazardous Polymerization: Has not been reported.
  
    | Section 11 - Toxicological Information | 
     
RTECS#:
     
CAS# 51-43-4:
DO2625000
     
LD50/LC50:
          CAS# 51-43-4:
      Skin, rat: LD50 = 62
          mg/kg;
.
     
Carcinogenicity:
       CAS#      51-43-4:
          Not listed by ACGIH, IARC, NTP, or CA Prop 65.
     
Epidemiology:
          No data available.
     
Teratogenicity:
          No data available.
     
Reproductive Effects:
Studies are reported in RTECs where injection of adrenaline
caused a variety of reproductive effects in animals.
     
Mutagenicity:
Mutagenic studies are reported in RTECs.
     
Neurotoxicity:
          No data available.
     
Other Studies:
  
    | Section 12 - Ecological Information | 
          No information available.
  
    | Section 13 - Disposal Considerations | 
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: CAS# 51-43-4: waste number
P042.
RCRA U-Series: None listed.
  
    | Section 14 - Transport Information | 
  |  | US DOT | Canada TDG | 
| Shipping Name: | Not regulated as a hazardous material | No information available. | 
| Hazard Class: |  |  | 
| UN Number: |  |  | 
| Packing Group: |  |  | 
  
    | Section 15 - Regulatory Information | 
 US FEDERAL
     
TSCA
     CAS# 51-43-4 is listed on the TSCA inventory.
        
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
        
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
        
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
        
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
        
CERCLA Hazardous Substances and corresponding RQs
     CAS# 51-43-4: 1000 lb final RQ; 454 kg final RQ
        
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
        
SARA Codes
     CAS # 51-43-4: immediate, delayed.
        
Section 313
     No chemicals are reportable under Section 313.
     
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
     
Clean Water Act:
     None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
     None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
     
OSHA:
     None of the chemicals in this product
are considered highly hazardous by OSHA.
 
STATE
          CAS#      51-43-4 can be found on the
     following state right to know lists: New Jersey, Pennsylvania,
     Massachusetts.
 
California Prop 65
     
California No Significant Risk Level:
     None of the chemicals in this product are listed.
 
European/International Regulations
     European Labeling in Accordance with EC Directives
          Hazard Symbols:
      T
          
Risk Phrases:
     R 23/24/25  Toxic by inhalation, in contact with skin and if          
     swallowed.                                                            
     R 33  Danger of cumulative effects.                                   
          
Safety Phrases:
     S 23  Do not inhale gas/fumes/vapour/spray.                           
     S 24/25  Avoid contact with skin and eyes.                            
   
WGK (Water Danger/Protection)
     CAS# 51-43-4: 3
   Canada - DSL/NDSL
     CAS# 51-43-4 is listed on Canada's DSL List.
   Canada - WHMIS
     This product has a WHMIS classification of D1A, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
   Canadian Ingredient Disclosure List
  
    | Section 16 - Additional Information | 
     MSDS Creation Date: 12/12/1997  
Revision #4 Date: 10/03/2005
     The information above is believed to be accurate and represents the best
     information currently available to us. However, we make no warranty of
     merchantability or any other warranty, express or implied, with respect to
     such information, and we assume no liability resulting from its use. Users
     should make their own investigations to determine the suitability of the
     information for their particular purposes. In no event shall Fisher be liable
     for any claims, losses, or damages of any third party or for lost profits
     or any special, indirect, incidental, consequential or exemplary
     damages, howsoever arising, even if Fisher has been advised of
     the possibility of such damages.